Lymphogranuloma venereum

Eckbo et al discuss five things to know about lymphogranuloma venereum (LGV). LGV is an aggressive, sexually transmitted infection caused by specific strains of Chlamydia trachomatis. Though LGV can be asymptomatic, the most common presentation is proctitis syndrome, whereby direct anal inoculation...

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Bibliographic Details
Published in:Canadian Medical Association journal (CMAJ) 2021-12, Vol.193 (49), p.E1889-E1889
Main Authors: Eckbo, Eric J, Hedgcock, Malcolm, Grennan, Troy
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - therapeutic use
Antibiotics
Anus
Canada - epidemiology
Causes of
Chlamydia
Chlamydia infections
Diagnosis
Diagnostic tests
Doxycycline - therapeutic use
Drug therapy
Epidemiology
Humans
Infections
Laboratories
Lymphadenopathy
Lymphogranuloma Venereum - diagnosis
Lymphogranuloma Venereum - drug therapy
Lymphogranuloma Venereum - epidemiology
Medical diagnosis
Practice
Public health
Sexual Partners
Sexually Transmitted Diseases, Bacterial - diagnosis
Sexually Transmitted Diseases, Bacterial - drug therapy
Sexually Transmitted Diseases, Bacterial - epidemiology
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Summary:Eckbo et al discuss five things to know about lymphogranuloma venereum (LGV). LGV is an aggressive, sexually transmitted infection caused by specific strains of Chlamydia trachomatis. Though LGV can be asymptomatic, the most common presentation is proctitis syndrome, whereby direct anal inoculation results in painful hemorrhagic proctitis, often mimicking inflammatory bowel disease. Swabs should be inserted 2 to 3 cm into the anal canal; alternatively, swabs can be collected by direct visualization during anoscopy. Lymph node aspirates and swabs of suspicious genital lesions can also be sent for NAAT. Canadian guidelines recommend oral doxycycline (100 mg, twice a day) for 21 days as first-line treatment.
ISSN:0820-3946
1488-2329
DOI:10.1503/cmaj.210853