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Results of the Seventh Scientific Workshop of ECCO: Precision Medicine in IBD—Disease Outcome and Response to Therapy

Abstract Inflammatory bowel diseases [IBD] are a heterogeneous spectrum with two extreme phenotypes, Crohn’s disease [CD] and ulcerative colitis [UC], which both represent numerous phenotypical variations. Hence, we should no longer approach all IBD patients similarly, but rather aim to rethink clin...

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Bibliographic Details
Published in:Journal of Crohn's and colitis 2021-09, Vol.15 (9), p.1431-1442
Main Authors: Verstockt, Bram, Noor, Nurulamin M, Marigorta, Urko M, Pavlidis, Polychronis, Deepak, Parakkal, Ungaro, Ryan C
Format: Article
Language:English
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Summary:Abstract Inflammatory bowel diseases [IBD] are a heterogeneous spectrum with two extreme phenotypes, Crohn’s disease [CD] and ulcerative colitis [UC], which both represent numerous phenotypical variations. Hence, we should no longer approach all IBD patients similarly, but rather aim to rethink clinical classifications and modify treatment algorithms to usher in a new era of precision medicine in IBD. This scientific ECCO workshop aims to provide a state-of-the-art overview on prognostic and predictive markers, shed light on key questions in biomarker development, propose best practices in IBD biomarker development [including trial design], and discuss the potential for multi-omic data integration to help drive further advances to make precision medicine a reality in IBD.
ISSN:1873-9946
1876-4479
DOI:10.1093/ecco-jcc/jjab050