Perceived HIV Treatment Norms Modify the Association Between HIV-Related Stigma and Adherence to Antiretroviral Therapy Among Persons Living with HIV in Baltimore, Maryland

Adherence to antiretroviral therapy (ART) is associated with reduced HIV-related morbidity/mortality and ongoing transmission; however, the extent to which this association is modified by perceived HIV treatment norms is unknown. 270 PLWH completed a survey to assess demographics, risk behaviors, st...

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Bibliographic Details
Published in:AIDS and behavior 2022-02, Vol.26 (2), p.537-548
Main Authors: Rudolph, Abby E., Dembo, Robert S., Tobin, Karin, Latkin, Carl
Format: Article
Language:English
Subjects:
Antiretroviral agents
Antiretroviral drugs
Antiretroviral therapy
Baltimore - epidemiology
Demography
Drug therapy
Families & family life
Friendship
Health behavior
Health Psychology
HIV
HIV Infections - drug therapy
Human immunodeficiency virus
Humans
Infectious Diseases
Medication Adherence
Medicine
Medicine & Public Health
Morbidity
Norms
Optimization
Original Paper
Patient compliance
Prescription drugs
Public Health
Risk assessment
Risk behavior
Risk taking
Social Stigma
Statistical analysis
Stigma
Treatment compliance
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Summary:Adherence to antiretroviral therapy (ART) is associated with reduced HIV-related morbidity/mortality and ongoing transmission; however, the extent to which this association is modified by perceived HIV treatment norms is unknown. 270 PLWH completed a survey to assess demographics, risk behaviors, stigma, ART adherence, and perceived HIV treatment norms (Baltimore, 2014–2017). We used modified Poisson regression to examine effect modification by perceived HIV treatment norms. The association between HIV-related stigma and ART adherence was modified by perceived HIV treatment norms. Among individuals who perceived that friends/family were sub-optimally adherent, HIV-related stigma was negatively associated with ART adherence (Adjusted Risk Ratio [ARR] = 0.36; 95%CI 0.15–0.87). Among those who perceived optimal adherence among friends/family, the relationship between HIV-related stigma and ART adherence was not statistically significant (ARR = 1.07; 95%CI 0.65–1.76). Interventions to improve ART adherence among those who are sub-optimally adherent could focus on increasing perceptions of ART adherence among their friends/family.
ISSN:1090-7165
1573-3254
DOI:10.1007/s10461-021-03409-3