Detailed videocapillaroscopic microvascular changes detectable in adult COVID-19 survivors

COVID-19 is a multisystem disease that causes endothelial dysfunction and organ damage. Aim of the study was to evaluate the microvascular status in COVID-19 survivors with past different disease severity, in comparison with age and sex-matched primary Raynaud's phenomenon (PRP) patients and co...

Full description

Saved in:
Bibliographic Details
Published in:Microvascular research 2022-07, Vol.142, p.104361-104361, Article 104361
Main Authors: Sulli, Alberto, Gotelli, Emanuele, Bica, Pietro Francesco, Schiavetti, Irene, Pizzorni, Carmen, Aloè, Teresita, Grosso, Marco, Barisione, Emanuela, Paolino, Sabrina, Smith, Vanessa, Cutolo, Maurizio
Format: Article
Language:English
Subjects:
Adult
Aged
Capillaries
COVID-19
COVID-19 - diagnosis
Endothelial cells
Glucocorticoids
Humans
Microcirculation
Microscopic Angioscopy
Middle Aged
Nailfold capillaroscopy
Nails - blood supply
Raynaud's phenomenon
SARS-CoV-2
Survivors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:COVID-19 is a multisystem disease that causes endothelial dysfunction and organ damage. Aim of the study was to evaluate the microvascular status in COVID-19 survivors with past different disease severity, in comparison with age and sex-matched primary Raynaud's phenomenon (PRP) patients and control subjects (CNT), including possible effects of concomitant therapies. Sixty-one COVID-19 survivors (mean age 58 ± 13 years, mean days from disease onset 126 ± 53 and mean days from recovery 104 ± 53), thirty-one PRP patients (mean age 59 ± 15 years, mean disease duration 11 ± 10 years) and thirty CNT (mean age 58 ± 13 years) underwent nailfold videocapillaroscopy (NVC) examination. The following capillaroscopic parameters were searched and scored (0–3): dilated capillaries, giant capillaries, isolated microhemorrhages, capillary ramifications (angiogenesis) and capillary number, including absolute capillary number per linear millimeter at the nailfold bed. The mean nailfold capillary number per linear millimeter was significantly lower in COVID-19 survivors when compared with PRP patients and CNT (univariate and multivariate analysis p 
ISSN:0026-2862
1095-9319
DOI:10.1016/j.mvr.2022.104361