Real-World LEAP Implementation

Purpose of Review In 2015, findings from the Learning Early About Peanut allergy (LEAP) trial provided the first convincing evidence that peanut allergy may be preventable through early peanut introduction into the infant diet. Here we discuss implementation of the LEAP study findings around the wor...

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Bibliographic Details
Published in:Current allergy and asthma reports 2021-06, Vol.22 (6), p.61-66
Main Authors: Koplin, Jennifer J., Soriano, Victoria X., Peters, Rachel L.
Format: Article
Language:English
Subjects:
Allergens
Allergology
Arachis
Food allergies
Food Allergy (E Kim
Food Allergy (E Kim, Section Editor)
Food Hypersensitivity - epidemiology
Food Hypersensitivity - prevention & control
Humans
Infant
Medicine
Medicine & Public Health
Peanut Hypersensitivity - epidemiology
Peanut Hypersensitivity - prevention & control
Prevalence
Section Editor
Topical Collection on Food Allergy
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Summary:Purpose of Review In 2015, findings from the Learning Early About Peanut allergy (LEAP) trial provided the first convincing evidence that peanut allergy may be preventable through early peanut introduction into the infant diet. Here we discuss implementation of the LEAP study findings around the world and emerging evidence of the impacts on infant feeding and food allergy. Recent Findings The LEAP findings led to rapid changes in allergy prevention guidelines internationally to recommend early peanut introduction. There is now emerging evidence that this has been followed by a substantial increase in early peanut introduction to infants. Studies investigating the impact of these changes in infant feeding practices on the prevalence of peanut allergy are underway. Summary The LEAP trial represented a significant step forwards in food allergy prevention and new research over the past 5 years has provided insights into how best to implement this intervention in the real world.
ISSN:1529-7322
1534-6315
1534-6315
DOI:10.1007/s11882-022-01032-3