Impact of a Novel Training Approach on Hemodynamic and Vascular Profiles in Older Adults

Exercise training beneficially moderates the effects of vascular aging. This study compared the efficacy of Peripheral Remodeling through Intermittent Muscular Exercise (PRIME), a novel training regimen, versus aerobic training on hemodynamic profiles in participants ≥70 years at risk for losing fun...

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Bibliographic Details
Published in:Journal of aging and physical activity 2022-04, Vol.30 (2), p.196-203
Main Authors: Woessner, Mary N, Welsch, Michael A, VanBruggen, Mitch D, Johannsen, Neil M, Credeur, Daniel P, Pieper, Carl F, Sloane, Richard, Earnest, Conrad P, Ortiz De Zevallos Munoz, Joaquin, Church, Timothy S, Ravussin, Eric, Kraus, William E, Allen, Jason D
Format: Article
Language:English
Subjects:
Aerobic exercise
Aerobics
Aged
Aged, 80 and over
Aging
Blood pressure
Blood Pressure - physiology
Efficacy
Exercise
Exercise - physiology
Female
Hemodynamics
Humans
Intermittent
Male
Older people
Physical fitness
Resistance Training
Strength training
Vascular Stiffness
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Summary:Exercise training beneficially moderates the effects of vascular aging. This study compared the efficacy of Peripheral Remodeling through Intermittent Muscular Exercise (PRIME), a novel training regimen, versus aerobic training on hemodynamic profiles in participants ≥70 years at risk for losing functional independence. Seventy-five participants (52 females, age: 76 ± 5 years) were assessed for hemodynamic and vascular function at baseline, after 4 weeks of either PRIME or aerobic training (Phase 1) and again after a further 8 weeks of aerobic and resistance training (Phase 2). Data were analyzed using 2 × 2 repeated-measures analysis of variance models on the change in each dependent variable. PRIME demonstrated reductions in brachial and aortic mean arterial pressure and diastolic blood pressure (p < .05) from baseline after Phase 1, which were sustained throughout Phase 2. Earlier and greater reductions in blood pressure following PRIME support the proposal that peripheral muscular training could beneficial for older individuals commencing an exercise program.
ISSN:1063-8652
1543-267X
1543-267X
DOI:10.1123/japa.2020-0509