Serial blood concentration of polyethoxylated tallow amine and clinical presentations in acute herbicide poisoning

Most commercially available herbicides contain surfactants as co-formulants to increase adhesion and absorption by plant leaves. Ethoxylated amines, one of the most used surfactants, are non-ionic and derived from animal fats. They represent a class of surfactants with similar structural features, i...

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Bibliographic Details
Published in:World journal of emergency medicine 2022, Vol.13 (4), p.305-308
Main Authors: Park, Jungsoo, Kim, Sun Cheun, Jeon, Youngjoon, Cho, Yong Chul, Kang, Changshin, You, Yeonho, Ann, Hong Joon, Ryu, Seung, Lee, Jihan, Jeong, Wonjoon
Format: Article
Language:English
Subjects:
Amines
Food
Herbicides
Poisoning
Research Letter
Safety and security measures
Surface active agents
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Summary:Most commercially available herbicides contain surfactants as co-formulants to increase adhesion and absorption by plant leaves. Ethoxylated amines, one of the most used surfactants, are non-ionic and derived from animal fats. They represent a class of surfactants with similar structural features, including polyethoxylated tallow amine (POEA). POEA is widely used in glyphosate, glufosinate-containing herbicides. In 2015, the European Food Safety Society (EFSA) concluded that POEA was more toxic than glyphosate when tested in glyphosate-based formulations. [1] They also attributed the poisoning following ingestion by humans to the presence of POEA. However, there are few in vivo metabolic studies on post-acute herbicide poisoning in humans. Therefore, we investigated the change in the blood concentration of POEA over time and the clinical presentations in patients with acute herbicide poisoning.
ISSN:1920-8642
DOI:10.5847/wjem.j.1920-8642.2022.061