Untangling the relationship between hemoglobin, peak troponin level, and mortality in patients with myocardial infarction

Patients with a history of myocardial infarction (MI) and lower admission hemoglobin (aHb) levels have a worse outcome than patients with higher aHb, but lower or similar peaks in enzymatic infarct size. Hemoglobin levels are positively correlated with body surface area (BSA), which is positively co...

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Bibliographic Details
Published in:Biomolecules & biomedicine 2022-09, Vol.22 (5), p.791-797
Main Authors: Kanic, Vojko, Kompara, Gregor, Suran, David, Glavnik Poznic, Nina
Format: Article
Language:English
Subjects:
baseline hemoglobin
body surface area
Development and progression
Health aspects
Heart attack
Hemoglobin
infarct size
Measurement
myocardial infarction
myocardial injury
Patient outcomes
percutaneus coronary intervention
Prognosis
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Summary:Patients with a history of myocardial infarction (MI) and lower admission hemoglobin (aHb) levels have a worse outcome than patients with higher aHb, but lower or similar peaks in enzymatic infarct size. Hemoglobin levels are positively correlated with body surface area (BSA), which is positively correlated with cardiac mass. We hypothesized that patients with lower aHb suffer comparatively greater myocardial injury. We examined the relationships between aHb, and troponin (Tn) normalized to BSA (Tn/BSA) and its association with 30-day mortality. Data from 6055 patients, who were divided into seven groups based on their aHb at 10g/L intervals, were analyzed, and the groups were compared. The relationships between aHb and Tn/BSA and between Tn/BSA and 30-day mortality were assessed. Patients with higher aHb levels had greater BSA (p
ISSN:1512-8601
2831-0896
1840-4812
2831-090X
DOI:10.17305/bjbms.2021.6744