Comparative efficacy and complications of long-acting and intermediate-acting insulin regimens for adults with type 1 diabetes: an individual patient data network meta-analysis

ObjectiveTo examine the comparative efficacy and complications of long-acting and intermediate-acting insulin for different patient characteristics for type 1 diabetes mellitus (T1DM).DesignSystematic review and individual patient data (IPD) network meta-analysis (NMA).Data sourcesMEDLINE, EMBASE an...

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Bibliographic Details
Published in:BMJ open 2022-11, Vol.12 (11), p.e058034
Main Authors: Veroniki, Areti Angeliki, Seitidis, Georgios, Stewart, Lesley, Clarke, Mike, Tudur-Smith, Catrin, Mavridis, Dimitris, Yu, Catherine H, Moja, Lorenzo, Straus, Sharon E, Tricco, Andrea C
Format: Article
Language:English
Subjects:
Adult
Bias
Clinical significance
Diabetes
DIABETES & ENDOCRINOLOGY
Diabetes and Endocrinology
Diabetes Mellitus, Type 1 - drug therapy
EPIDEMIOLOGY
Funding
Glycated Hemoglobin
Humans
Hypoglycemia
Hypoglycemia - chemically induced
Hypoglycemic Agents - therapeutic use
Insulin
Insulin - therapeutic use
Insulin Glargine - therapeutic use
Insulin, Isophane
Insulin, Long-Acting - therapeutic use
Meta-analysis
Patients
PUBLIC HEALTH
Systematic review
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