Gas in scattering media absorption spectroscopy as a potential tool in neonatal respiratory care

Gas in scattering media absorption spectroscopy (GASMAS) is a novel optical technology employing near-infrared light. It has a potential use in the medical setting as a monitoring and diagnostic tool by detecting molecular oxygen within gas pockets and thus may be a useful adjunct in respiratory mon...

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Bibliographic Details
Published in:Pediatric research 2022-11, Vol.92 (5), p.1240-1246
Main Authors: Panaviene, Jurate, Pacheco, Andrea, Schwarz, Christoph E., Grygoryev, Konstantin, Andersson-Engels, Stefan, Dempsey, Eugene M.
Format: Article
Language:English
Subjects:
Gases
Humans
Infant, Newborn
Medicine
Medicine & Public Health
Monitoring, Physiologic - methods
Oxygen - chemistry
Pediatric Surgery
Pediatrics
Respiratory Rate
Review
Review Article
Spectrum analysis
Spectrum Analysis - methods
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Summary:Gas in scattering media absorption spectroscopy (GASMAS) is a novel optical technology employing near-infrared light. It has a potential use in the medical setting as a monitoring and diagnostic tool by detecting molecular oxygen within gas pockets and thus may be a useful adjunct in respiratory monitoring. GASMAS has potential advantages over other monitoring devices currently used in clinical practice. It is a non-invasive, continuous, non-ionising technology and provides unique information about molecular oxygen content inside the lungs. GASMAS may have a future role in optimising respiratory management of neonates in different clinical scenarios such as monitoring cardiorespiratory transition in the delivery room, assessing surfactant deficiency, and optimising endotracheal tube positioning. This article aims to summarise current evidence exploring GASMAS application in a neonate, discuss possible clinical benefits, and compare with other devices that are currently used in neonatal care. Impact This article presents a novel optical technique to measure lung oxygen concentrations that may have important clinical uses. This review summarises the current literature investigating the concept of optical lung oxygen measurement. Information from this review can guide researchers in future studies.
ISSN:0031-3998
1530-0447
DOI:10.1038/s41390-022-02110-y