Investigations on mediterranean Kala Azar. VI.—Canine visceral leishmaniasis

Following the discovery of canine visceral Leishmaniasis in Tunis by Nicolle and Comte (1908), an extensive literature has developed dealing particularly with the possible relationship between human and canine Leishmaniasis. Most authors, following Nicolle, consider Leishmania infantum, to be the ca...

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Bibliographic Details
Published in:Proceedings of the Royal Society of London. Series B, Containing papers of a biological character Containing papers of a biological character, 1932-05, Vol.110 (768), p.402-412
Main Authors: Adler, Saul, Theodor, O.
Format: Article
Language:English
Subjects:
Canines
Dermis
Dogs
Hair follicles
Humans
Infections
Macrophages
Skin
Spleen
Visceral leishmaniasis
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Summary:Following the discovery of canine visceral Leishmaniasis in Tunis by Nicolle and Comte (1908), an extensive literature has developed dealing particularly with the possible relationship between human and canine Leishmaniasis. Most authors, following Nicolle, consider Leishmania infantum, to be the causative organism of both human and canine Kala Azar. In the case of cutaneous Leishmaniasis, L. tropica has been conclusively proved by direct experiment to be the causative organism in both man and dog (1930), but in this case there is no evidence that the dog serves as a reservoir of the human disease. It is more likely that where human and canine cutaneous Leishmaniasis co-exist, human beings serve as a reservoir from which dogs are infected (1929). It is, however, difficult to carry out similar direct experiments with visceral Leishmaniasis, for human adults are naturally immune to Mediterranean Kala Azar.
ISSN:0950-1193
2053-9185
DOI:10.1098/rspb.1932.0035