Chiral discrimination of α-amino acids with a C2-symmetric homoditopic receptorElectronic supplementary information (ESI) available: Synthetic route and characterization of receptor (S)-1, 19F and 1H NMR spectra of (S)-1-Ala, 19F of (S)-1-amino acids' adducts, and ITC data of (S)-1-Ala adducts. See DOI: 10.1039/b919957h

• Main Authors: Sambasivan, Sunderraman, Kim, Dae-sik, Ahn, Kyo Han
• Format: Article
• Language: English
• ISSN: 1359-7345; 1364-548X
• DOI: 10.1039/b919957h

Chiral discrimination of α-amino acids has been realized by a C 2 -symmetric homoditopic receptor, which is based on a binaphthyl chiral skeleton with 2,2′diisopropoxy substituents and a common binding side arm, ( o -carboxamido)-trifluoroacetophenone moiety, in the 3,3′-positions, which recognizes α-amino acids as their amino carboxylate forms through formation of stabilized adducts. Chiral discrimination of α-amino acids has been realized by a C 2 -symmetric homoditopic receptor, which is based on a binaphthyl chiral skeleton with 2,2′diisopropoxy substituents and a common binding side arm, ( o -carboxamido)-trifluoroacetophenone moiety, in the 3,3′-positions.