A new context for palladium mediated B-addition reaction: an open door to consecutive functionalization

Palladium metal-catalyzed boron addition to unsaturated carbon-carbon bonds provides an efficient and convenient route for the preparation of organoboranes, which are versatile intermediates for organic synthesis. Palladium complexes are responsible for the exclusive catalytic performance and eventu...

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Bibliographic Details
Published in:Organic & biomolecular chemistry 2010-06, Vol.8 (12), p.2667-2682
Main Authors: Pubill-Ulldemolins, Cristina, Bonet, Amadeu, Bo, Carles, Gulyás, Henrik, Fernández, Elena
Format: Article
Language:English
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Summary:Palladium metal-catalyzed boron addition to unsaturated carbon-carbon bonds provides an efficient and convenient route for the preparation of organoboranes, which are versatile intermediates for organic synthesis. Palladium complexes are responsible for the exclusive catalytic performance and eventually allow access to selectively functionalized molecules by catalytic consecutive tandem sequences. The final objective is to find suitable palladium complexes that make it possible to perform a one-pot sequential reaction (B-addition/functionalization) by means of a multifaceted palladium catalyst. Mechanistic insights into the concatenated reactions through B chemistry are required if one wants to understand the experimental results. Highlighting the great interest in the application of organoboranes in C-C bond formation, this perspective provides the reader with the criteria to design consecutive tandem organoboron formation/C-C coupling reactions by means of multifaceted palladium catalytic systems.
ISSN:1477-0520
1477-0539
DOI:10.1039/b924658b