Pharmaceutical cocrystals: walking the talk

Pharmaceutical cocrystals belong to a sub-class of cocrystals wherein one of the components is a drug molecule (or an active pharmaceutical ingredient, API) and the second is a benign food or drug grade additive (generally regarded as safe, GRAS). The two components are hydrogen-bonded in a fixed st...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2016-06, Vol.52 (54), p.8342-836
Main Authors: Bolla, Geetha, Nangia, Ashwini
Format: Article
Language:English
Subjects:
active pharmaceutical ingredients
Bioavailability
Biological Availability
chemical reactions
color
Crystallization - methods
drug toxicity
Drugs
engineering
flavanoids
functional foods
GRAS substances
half life
hardness
Hydration
hydrogen bonding
Mechanical Phenomena
melting point
Melting points
multiple drug resistance
Permeability
Pharmaceutical Preparations - chemistry
Pharmaceutical Preparations - metabolism
Pharmaceuticals
pharmacokinetics
photostability
plasticity
polyphenols
Solubility
Stability
Transition Temperature
X-ray diffraction
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