Structure-specific antitumor effects and potential gut microbiota-involved mechanisms of ginseng polysaccharides on B16F10 melanoma-bearing mice

Ginseng polysaccharides (GPs) have shown gut microbiota-related antitumor effects. However, the relation between their structures and antitumor functions remains unknown. Here, crude polysaccharide (GP-c) and its fractions neutral polysaccharide (GP-n) and pectin (GP-a) were prepared for structure c...

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Bibliographic Details
Published in:Food & function 2023-01, Vol.14 (2), p.796-89
Main Authors: Xie, Ni-Na, Wu, Cheng-Ying, Ge, Qiong, Zhou, Jing, Long, Fang, Mao, Qian, Li, Song-Lin, Shen, Hong
Format: Article
Language:English
Subjects:
Abundance
Acetic acid
Allobaculum
Animals
Anticancer properties
Antitumor activity
Bifidobacterium
Butyric acid
Ecosystem
Fatty acids
Fatty Acids, Volatile - pharmacology
Firmicutes
Fractions
Gastrointestinal Microbiome
Ginseng
Intestinal microflora
Melanoma
Mice
Microbiota
Molecular weight
Molecular weight distribution
Monosaccharides
Panax - chemistry
Pectin
Polysaccharides
Polysaccharides - pharmacology
Saccharides
Structural analysis
Structure-function relationships
Tumors
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