Association of hypertension and dyslipidaemia with increasing obesity in patients with Type 2 Diabetes Mellitus

The study was performed to estimate the association of hypertension and dyslipidaemia with increasing body weight and obesity in Type II diabetics of Lahore, Pakistan. An observational study was conducted by enrolling 2708 obese diabetics from four diabetes care centres of Lahore, Pakistan. Data was...

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Bibliographic Details
Published in:Brazilian Journal of Pharmaceutical Sciences 2019, Vol.55
Main Authors: Saleem, Zikria, Saeed, Hamid, Khan, Zohaib Abbas, Khan, Muhammad Imran Hassan, Hashmi, Furqan Khurshid, Islam, Muhammad, Bashir, Afzaal, Sadeeqa, Saleha
Format: Article
Language:English
Subjects:
Age
Blood pressure
Body mass index
Cardiovascular disease
Cholesterol
Coronary vessels
Demographics
Diabetes
Disease prevention
Dyslipidaemia
Frequency distribution
Glucose
HbA1c
Hemoglobin
Hospitals
Hypertension
Kidney diseases
Lahore/Pakistan
Metabolic disorders
Obesity
Overweight
Patients
PHARMACOLOGY & PHARMACY
Population
Type II Diabetes Mellitus
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Summary:The study was performed to estimate the association of hypertension and dyslipidaemia with increasing body weight and obesity in Type II diabetics of Lahore, Pakistan. An observational study was conducted by enrolling 2708 obese diabetics from four diabetes care centres of Lahore, Pakistan. Data was collected for a period of 7 months. Associations were estimated using chi-square, binary and multinomial logistic regression. Data suggested that blood pressure, systolic and diastolic, exhibited continual increase with increasing body weight and obesity class in diabetes patients with 41.8% increase in the prevalence of hypertension in obesity class III subjects (OR; 1.91, p=0.02). Likewise, triglycerides and total cholesterol exhibited continual increase in their mean values with increasing obesity, i-e., an overall increase in the prevalence of dyslipidaemia of 27.2% in obesity class 3 subjects (OR; 1.94, p=0.29). Taken together, this data suggested that hypertension is potentially associated with increasing obesity in diabetics, while dyslipidaemia demonstrated plausible association only with obesity class 3.
ISSN:2175-9790
1984-8250
2175-9790
DOI:10.1590/s2175-97902019000118136