Expanding the frontier of CAR therapy: comparative insights into CAR-T, CAR-NK, CAR-M, and CAR-DC approaches

Chimeric antigen receptor (CAR) therapies have demonstrated remarkable clinical efficacy in hematological malignancies, validating their therapeutic potential. However, challenges such as therapeutic resistance and limited accessibility hinder their broader application. To overcome these limitations...

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Bibliographic Details
Published in:Annals of hematology 2025-09, Vol.104 (9), p.4305-4317
Main Authors: Zhang, Yiling, Hu, Rong, Xie, Xiaoling, Li, Yuhua
Format: Article
Language:English
Subjects:
Animals
Antibodies
Antigens
Apoptosis
Cell- and Tissue-Based Therapy - methods
Clinical trials
Cytokine Release Syndrome - etiology
Cytokines
Cytotoxicity
Dendritic Cells - immunology
Dendritic Cells - transplantation
DNA methylation
Epigenetics
Hematologic Neoplasms - immunology
Hematologic Neoplasms - therapy
Hematology
Humans
Immune system
Immunotherapy, Adoptive - adverse effects
Immunotherapy, Adoptive - methods
Immunotherapy, Adoptive - trends
Killer Cells, Natural - immunology
Killer Cells, Natural - transplantation
Lymphocytes
Lymphoma
Macrophages - immunology
Macrophages - transplantation
Medicine
Medicine & Public Health
Multiple myeloma
Oncology
Receptors, Chimeric Antigen - immunology
Review
T cell receptors
Toxicity
Transcription factors
Citations: Items that this one cites
Online Access:Get full text
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