Distribution of local anesthetic in axillary brachial plexus block: A clinical and Magnetic Resonance Imaging Study

• Published in: Anesthesiology (Philadelphia) 2002-06, Vol.96 (6), p.1315-1324
• Main Authors: KLAASTAD, Øivind, SMEDBY, Orjan, THOMPSON, Gale E, TILLUNG, Terje, HOL, Per Kristian, RØTNES, Jan S, BRODAL, Per, BREIVIK, Harald, HETLAND, Karl R, FOSSE, Erik T
• Format: Article
• Language: English
• Subjects: Adult; Aged; Anesthesia; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Anesthetics, Local - pharmacokinetics; Biological and medical sciences; Brachial Plexus; Female; Humans; Local anesthesia. Pain (treatment); Magnetic Resonance Imaging; Male; Medical sciences; MEDICIN; MEDICINE; Middle Aged; Nerve Block
• ISSN: 0003-3022; 1528-1175; 1528-1175
• DOI: 10.1097/00000542-200206000-00009

There is an unsettled discussion about whether the distribution of local anesthetic is free or inhibited when performing brachial plexus blocks. This is the first study to use magnetic resonance imaging (MRI) to help answer this question. Thirteen patients received axillary block by a catheter-nerve stimulator technique. After locating the median nerve, a total dose of 50 ml local anesthetic was injected via the catheter in four divided doses of 1, 4, 15, and 30 ml. Results of sensory and motor testing were compared with the spread of local anesthetic as seen by MRI scans taken after each dose. The distribution of local anesthetic was described with reference to a 20-mm diameter circle around the artery. Thirty minutes after the last dose, only two patients demonstrated analgesia or anesthesia in the areas of the radial, median, and ulnar nerve. At that time, eight of the patients had incomplete spread of local anesthetic around the artery, as seen by MRI. Their blocks were significantly poorer than those of the five patients with complete filling of the circle, although incomplete blocks were also present in the latter group. This study demonstrated that MRI is useful in examining local anesthetic distribution in axillary blocks because it can show the correlation between MRI distribution pattern and clinical effect. The cross-sectional spread of fluid around the brachial-axillary artery was often incomplete-inhibited, and the clinical effect often inadequate.