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Implications of mortality transition for primary health care in rural South Africa: a population-based surveillance study

Summary Background In southern Africa, a substantial health transition is underway, with the heavy burden of chronic infectious illness (HIV/AIDS and tuberculosis) paralleled by the growing threat of non-communicable diseases. We investigated the extent and nature of this health transition and consi...

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Published in:The Lancet (British edition) 2008-09, Vol.372 (9642), p.893-901
Main Authors: Tollman, Stephen M, Prof, Kahn, Kathleen, MD, Sartorius, Benn, MSc, Collinson, Mark A, MSc, Clark, Samuel J, PhD, Garenne, Michel L, PhD
Format: Article
Language:English
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Summary:Summary Background In southern Africa, a substantial health transition is underway, with the heavy burden of chronic infectious illness (HIV/AIDS and tuberculosis) paralleled by the growing threat of non-communicable diseases. We investigated the extent and nature of this health transition and considered the implications for primary health care. Methods Health and sociodemographic surveillance started in the Agincourt subdistrict, rural South Africa, in 1992. In a population of 70 000, deaths (n=6153) were rigorously monitored with a validated verbal autopsy instrument to establish probable cause. We used age-standardised analyses to investigate the dynamics of the mortality transition by comparing the period 2002–05 with 1992–94. Findings Mortality from chronic non-communicable disease ranked highest in adults aged 50 years and older in 1992–94 (41% of deaths [123/298]), whereas acute diarrhoea and malnutrition accounted for 37% of deaths (59/158) in children younger than 5 years. Since then, all-cause mortality increased substantially (risk ratio 1·87 [95% CI 1·73–2·03]; p
ISSN:0140-6736
1474-547X
1474-547X
DOI:10.1016/S0140-6736(08)61399-9