Lifestyle Intervention for Type 2 Diabetes Risk Reduction: Using the Diabetes Prevention Program to Inform New Directions in Pediatric Research

ABSTRACT The primary means of reducing risk for type 2 diabetes in adults include establishing and maintaining healthy lifestyle behaviours (e.g. diet and physical activity) and achieving and maintaining a healthy body weight. The evidence to support this approach has been derived from a variety of...

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Bibliographic Details
Published in:Canadian journal of diabetes 2007, Vol.31 (3), p.242-251
Main Authors: Franks, Paul W., PhD MPhil, Huang, MS,Terry T.-K., PhD MPH, Ball, Geoff D.C., PhD RD
Format: Article
Language:English
Subjects:
Adolescent
adolescents
child
Diabète de type 2
Endocrinology & Metabolism
enfants
essai clinique randomisé
Other
pediatric
prevention
prévention
randomized clinical trial
youth
études menées chez les enfants
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Summary:ABSTRACT The primary means of reducing risk for type 2 diabetes in adults include establishing and maintaining healthy lifestyle behaviours (e.g. diet and physical activity) and achieving and maintaining a healthy body weight. The evidence to support this approach has been derived from a variety of studies; among this body of research, the Diabetes Prevention Program (DPP) has arguably been the most influential and informative. While data from the DPP demonstrate that type 2 diabetes can be prevented or delayed in adults by making lifestyle modifications, to date, there is little evidence from pediatric studies to demonstrate the benefits of a similar approach. The aim of this review is to highlight key findings from the DPP related to the role of lifestyle interventions for preventing type 2 diabetes and reducing metabolic health risk. As in adults, intensive lifestyle modification is likely to be among the most effective therapies for diabetes prevention in children and youth. Given the recent marked increases in the prevalence of obesity and type 2 diabetes in the pediatric population, evidence-guided research and lifestyle recommendations based on empirical evidence that focus on preventing type 2 diabetes in children and youth are urgently needed.
ISSN:1499-2671
2352-3840
DOI:10.1016/S1499-2671(07)13011-2