Let's talk turkey: immune competence in domestic and wild fowl

A major goal in conservation and evolutionary biology is to determine whether endangered populations harbour sufcient genetic variation to maintain effective protection against harmful pathogens and to understand what factors contribute to maintaining genetic variance for disease resistance. In vert...

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Bibliographic Details
Published in:Heredity 2011-08, Vol.107 (2), p.103-104
Main Authors: Husby, A, Ekblom, R, Qvarnström, A
Format: Article
Language:English
Subjects:
and
Animals
Disease resistance
Endangered populations
Evolutionary biology
Genetic diversity
Genetic variance
Genetic Variation
Genetics
Immunology
Major Histocompatibility Complex - genetics
Turkeys - genetics
Wildfowl
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Summary:A major goal in conservation and evolutionary biology is to determine whether endangered populations harbour sufcient genetic variation to maintain effective protection against harmful pathogens and to understand what factors contribute to maintaining genetic variance for disease resistance. In vertebrates, the major histocompatibility complex (MHC) is an important genetic region involved in immune responses and it is the most polymorphic and gene-dense region in the whole genome (Kelley et al., 2005). In birds, the MHC-B locus contains most of the genes responsible for antigen processing and presentation and is considered to be the homologue to the mammalian MHC.
ISSN:0018-067X
1365-2540
1365-2540
DOI:10.1038/hdy.2010.176