Inorganic arsenic in food products on the Swedish market and a risk-based intake assessment

• Published in: The Science of the total environment 2019-07, Vol.672, p.525-535
• Main Authors: Kollander, B., Sand, S., Almerud, P., Ankarberg, E. Halldin, Concha, G., Barregård, L., Darnerud, P.O.
• Format: Article
• Language: English
• Subjects: animals; cadmium; cohort; Environmental Sciences & Ecology; Fish; Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi; health; human exposure; Inorganic arsenic; Intake; population; pregnancy; Public Health, Global Health, Social Medicine and Epidemiology; Rice; Risk assessment; Shellfish; speciation; toxicity; water
• ISSN: 0048-9697; 1879-1026
• DOI: 10.1016/j.scitotenv.2019.03.289

Inorganic arsenic (iAs) and total arsenic (tAs) were determined in common food from the Swedish market. Special focus was on rice, fish and shellfish products. For the speciation of iAs the European standard EN:16802 based on anion exchange chromatography coupled to ICP-MS was used. The two market basket food groups cereals (including rice), and sweets and condiments (a mixed group of sugar, sweets, tomato ketchup and dressings), contained the highest iAs levels (means 9 and 7 μg iAs/kg), whereas other food groups, including fish, did not exceed 2 μg iAs/kg. Varying levels of iAs were found in separate samples of tomato ketchup, 2.4–26 μg/kg, and is suggested to be one reason of the rather high average level of iAs in the food group sweets and condiments. Some specific food products revealed iAs levels much higher, i.e. rice crackers 152 and Norway lobster 89 μg iAs/kg. The intake of iAs via food was estimated by data from two national consumption surveys, performed in 2010–11 (1797 adults) and 2003 (2259 children). The estimated median iAs intakes in adults and children were 0.047 and 0.095 μg/kg body weight and day, respectively. The iAs intake for rice eaters was about 1.4 times higher than for non-rice eaters. Validation of the consumption survey-based iAs intake, using food purchase and market basket data mainly from 2015, resulted in a per capita intake of a similar magnitude, i.e. 0.056 μg/kg body weight and day. The estimated cancer risk for adults using low-dose linear extrapolation is