Nodule detection in digital chest radiography: effect of nodule location

Most detection studies in chest radiography treat the entire chest image as a single background or divided into the two regions parenchyma and mediastinum. However, the different parts of the lung show great variations in attenuation and structure, leading to different amounts of quantum noise and s...

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Bibliographic Details
Published in:Radiation protection dosimetry 2005-01, Vol.114 (1-3), p.92-96
Main Authors: Håkansson, Markus, Båth, Magnus, Börjesson, Sara, Kheddache, Susanne, Flinck, Agneta, Ullman, Gustaf, Månsson, Lars Gunnar
Format: Article
Language:English
Subjects:
Anatomic
Computer-Assisted
diagnosis
Humans
Image Processing
Image Processing, Computer-Assisted
Lung
Lung - diagnostic imaging
Lung - pathology
Lung Neoplasms
Lung Neoplasms - diagnosis
Lung Neoplasms - diagnostic imaging
MEDICIN
MEDICINE
methods
Models, Anatomic
Monte Carlo Method
Observer Variation
pathology
Radiation
Radiographic Image Enhancement
Radiographic Image Enhancement - methods
Radiographic Image Interpretation
Radiographic Image Interpretation, Computer-Assisted - methods
radiography
Radiography - methods
Radiography, Thoracic - methods
Radiologi och bildbehandling
Radiology, Nuclear Medicine and Medical Imaging
ROC Curve
Scattering
Scattering, Radiation
Software
Thoracic
X-Rays
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Summary:Most detection studies in chest radiography treat the entire chest image as a single background or divided into the two regions parenchyma and mediastinum. However, the different parts of the lung show great variations in attenuation and structure, leading to different amounts of quantum noise and scattered radiation as well as different complexity. Detailed data on the difference in detectability in the different regions are of importance. The purpose of this study was to quantify the difference in detectability between different regions of a chest image. The chest X ray was divided into six different regions, where each region was considered to be uniform in terms of detectability. Thirty clinical chest images were collected and divided into the different regions. Simulated designer nodules with a full-width-at-fifth-maximum of 10 mm but with varying contrast were added to the images. An equal number of images lacking pathology were included and a receiver operating characteristic (ROC) study was conducted with five observers. Results show that the image contrast needed to obtain a constant value of Az (area under an ROC curve) differs by more than a factor of four between different regions.
ISSN:0144-8420
1742-3406
1742-3406
DOI:10.1093/rpd/nch524