Early-life Risk Factors for Adult Chronic Disease: Follow-up of a Cohort Born During 1964-1978 in an Urban Slum of Lahore, Pakistan

Evidence suggests that risk of chronic diseases may be programmed during the foetal and early life of the infant. With high rates of low birthweight coupled with a rapid nutritional transition, low-income countries are facing an epidemic of chronic diseases. Follow-up of a cohort of adults born duri...

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Bibliographic Details
Published in:Journal of health, population and nutrition population and nutrition, 2008-03, Vol.26 (1), p.12-21
Main Authors: Jalil, Fehmida, Moore, Sophie E, Butt, Nadeem S, Ashraf, Rifat N, Zaman, Shakila, Prentice, Andrew M, Hanson, Lars Å
Format: Article
Language:English
Subjects:
Adult
Age
Babies
Birth weight
Birth Weight - physiology
Birth weight, Low
Birthweight
Blood
Blood pressure
Blood Pressure - physiology
Body Mass Index
cardiovascular-disease
Chronic disease
Chronic Disease - epidemiology
Chronic diseases
Chronic illnesses
Chronic sickness
Cohort Studies
Developing countries
Disease models
Disease risk
Epidemiology
Fasting
Female
fetal origins
Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi
Follow-up studies
Glucose
Glucose intolerance
Glucose Intolerance - epidemiology
Glucose Intolerance - etiology
Health aspects
Humans
Hypertension - epidemiology
Hypertension - etiology
hypothesis
Infant
Infant Nutritional Physiological Phenomena
Infant, Newborn
Infants
LDCs
lipid-metabolism
Male
Maternal Nutritional Physiological Phenomena
NATURAL SCIENCES
NATURVETENSKAP
nutrition
Obesity
Original Papers
Pakistan
Pakistan - epidemiology
population
Pregnancy
Prenatal Exposure Delayed Effects
Prenatal Nutritional Physiological Phenomena
pressure
Public Health, Global Health, Social Medicine and Epidemiology
Quality of life
Risk Factors
Slum communities
Slums
Urban areas
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Summary:Evidence suggests that risk of chronic diseases may be programmed during the foetal and early life of the infant. With high rates of low birthweight coupled with a rapid nutritional transition, low-income countries are facing an epidemic of chronic diseases. Follow-up of a cohort of adults born during 1964-1978 in an urban slum in Lahore, Pakistan, is presented in this paper. In 695 of these adults (mean age=29.0 years, males=56%), blood pressure, fasting blood glucose, and body mass index (BMI) were measured to assess early-life predictors of risk of chronic diseases. Sixteen percent of the study population was born with a low birthweight (
ISSN:1606-0997
2072-1315