Prepregnancy maternal body mass index and venous thromboembolism: a population‐based cohort study

Objective To assess the relation between maternal body mass index (BMI) and pregnancy‐related venous thromboembolism (VTE). Design Cohort study. Setting and population A total of 2 449 133 women with singleton pregnancies who underwent delivery hospitalisation in California between 2008 and 2012. Me...

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Bibliographic Details
Published in:BJOG : an international journal of obstetrics and gynaecology 2019-04, Vol.126 (5), p.581-588
Main Authors: Butwick, AJ, Bentley, J, Leonard, SA, Carmichael, SL, El‐Sayed, YY, Stephansson, O, Guo, N
Format: Article
Language:English
Subjects:
Adult
Antepartum
Body Mass Index
Body weight
California - epidemiology
Cohort analysis
delivery
Female
Health risk assessment
Humans
Logistic Models
Medicin och hälsovetenskap
Obesity
Obesity - complications
Odds Ratio
Overweight
Population studies
Population-based studies
Postpartum
Pregnancy
Pregnancy Complications, Cardiovascular - epidemiology
Pregnancy Complications, Cardiovascular - etiology
Prevalence
Retrospective Studies
Risk Factors
Thromboembolism
Underweight
venous thromboembolism
Venous Thromboembolism - epidemiology
Venous Thromboembolism - etiology
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Summary:Objective To assess the relation between maternal body mass index (BMI) and pregnancy‐related venous thromboembolism (VTE). Design Cohort study. Setting and population A total of 2 449 133 women with singleton pregnancies who underwent delivery hospitalisation in California between 2008 and 2012. Methods Association of pre‐pregnancy BMI and the risk of an antepartum and postpartum VTE was examined using logistic regression, with normal BMI as reference. Main outcome measures Antepartum and postpartum VTE‐related hospitalisation. Results The prevalence of antepartum and postpartum VTE increased with increasing BMI (antepartum: 2.3, 3.0, 3.8, 4.2, 4.7, and 10.6 per 10 000 women for underweight, normal BMI, overweight, obesity class I, II, and III, respectively, P 
ISSN:1470-0328
1471-0528
1471-0528
DOI:10.1111/1471-0528.15567