Extremely preterm infants who are small for gestational age have a high risk of early hypophosphatemia and hypokalemia

Aim Electrolyte balances have not been sufficiently evaluated in extremely preterm infants after early parenteral nutrition. We investigated the risk of early hypophosphatemia and hypokalemia in extremely preterm infants born small for gestational age (SGA) who received nutrition as currently recomm...

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Bibliographic Details
Published in:Acta Paediatrica 2015-11, Vol.104 (11), p.1077-1083
Main Authors: Boubred, F, Herlenius, E, Bartocci, M, Jonsson, B, Vanpée, M
Format: Article
Language:English
Subjects:
Age Factors
Cohort Studies
Extremely low birthweight infants
Female
High protein intake
Humans
Hypokalemia - epidemiology
Hypokalemia - etiology
Hypophosphatemia
Hypophosphatemia - epidemiology
Hypophosphatemia - etiology
Infant, Extremely Premature
Infant, Newborn
Infant, Small for Gestational Age
Male
Medicin och hälsovetenskap
Parenteral Nutrition - adverse effects
Prospective Studies
Refeeding syndrome
Small for gestational age
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Summary:Aim Electrolyte balances have not been sufficiently evaluated in extremely preterm infants after early parenteral nutrition. We investigated the risk of early hypophosphatemia and hypokalemia in extremely preterm infants born small for gestational age (SGA) who received nutrition as currently recommended. Methods This prospective, observational cohort study included all consecutive extremely preterm infants born at 24–27 weeks who received high amino acids and lipid perfusion from birth. We evaluated the electrolyte levels of SGA infants and infants born appropriate for gestational age (AGA) during the first five days of life. Results The 12 SGA infants had lower plasma potassium levels from Day One compared to the 36 AGA infants and were more likely to have hypokalemia (58% vs 17%, p = 0.001) and hypophosphatemia (40% vs 9%, p 
ISSN:0803-5253
1651-2227
1651-2227
DOI:10.1111/apa.13093