Phytochemistry and larvicidal activity of Eucalyptus camaldulensisagainst malaria vector,Anopheles stephensi

Objective:To determine phytochemistry and larvicidal activity ofEucalyptus camaldulensis againstAnopheles stephensi.Methods:The chemical compositions of the leaf essential oils were analyzed using gas chromatography/mass spectrometry (GC/MS). The larvicidal activity of essential oils and extract of...

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Published in:亚太热带医药杂志（英文版） 2010 (11), p.841-845
Main Authors: Sedaghat Mohamad Medhi, SaneiAli Reza, Khnavi Mahnaz, Abai Mohammad Reza, Hadjiakhoondi Abbas, MohtaramiFatemeh, VatandoostHassan
Format: Article
Language:English
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Summary:Objective:To determine phytochemistry and larvicidal activity ofEucalyptus camaldulensis againstAnopheles stephensi.Methods:The chemical compositions of the leaf essential oils were analyzed using gas chromatography/mass spectrometry (GC/MS). The larvicidal activity of essential oils and extract of leaf were tested against 4th instar larvae of laboratory-rearedAnopheles stephensi.Results:GC/MS analyses identified the presence of28 compounds corresponding to 99.60%of the total oil. The main constituents in the leaf essential oil were1,8-cineole(69.46%), γ-Terpinene(15.10%), α-Pinene(5.47%)and Globulol(2%). The leaf extract and volatile oil exerted significant larvicidal activity withLC50 values of89.85 and397.75ppm, respectively. Clear dose-response relationships were established with the highest dose of320 ppm essential oil extract resulted almost100% mortality in the population.Conclusions:The larvicidal properties suggest that the essential oil of plant is a potential source of valuable larvicidal compounds against malaria vector and can be used as an alternative to synthetic insecticides.
ISSN:1995-7645