Associations of genetically predicted circulating insulin‐like growth factor‐1 and insulin‐like growth factor binding protein‐3 with bladder cancer risk

Insulin‐like growth factors (IGF) play important roles in carcinogenesis. The associations of circulating IGF‐1 and insulin‐like growth factor‐binding protein‐3 (IGFBP‐3) with the risks of bladder cancer remain unclear. In this large case control study of 2011 bladder cancer cases and 2369 heathy co...

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Bibliographic Details
Published in:	Molecular carcinogenesis 2021-11, Vol.60 (11), p.726-733
Main Authors:	Tsai, Chia‐Wen, Chang, Wen‐Shin, Xu, Yifan, Huang, Maosheng, Bau, Da‐Tian, Gu, Jian
Format:	Article
Language:	English
Subjects:	Aged Bladder cancer Cancer Carcinogenesis Case-Control Studies Female Genetic Association Studies Genetic diversity Genetic Predisposition to Disease genetic risk score Genome-wide association studies Genome-Wide Association Study Genomes Growth factors Humans IGF‐1 Insulin Insulin-Like Growth Factor Binding Protein 3 - blood Insulin-Like Growth Factor Binding Protein 3 - genetics Insulin-Like Growth Factor I - genetics Insulin-Like Growth Factor I - metabolism Insulin-like growth factors Male Mendelian randomization Mendelian Randomization Analysis - methods Middle Aged Polymorphism, Single Nucleotide Risk factors Single-nucleotide polymorphism SNP Urinary Bladder Neoplasms - blood Urinary Bladder Neoplasms - genetics
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