Cancer cell invasion and EMT marker expression: a three-dimensional study of the human cancer-host interface

Cancer cell invasion takes place at the cancer–host interface and is a prerequisite for distant metastasis. The relationships between current biological and clinical concepts such as cell migration modes, tumour budding and epithelial–mesenchymal transition (EMT) remains unclear in several aspects,...

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Bibliographic Details
Published in:The Journal of pathology 2014-11, Vol.234 (3), p.410-422
Main Authors: Bronsert, P, Enderle-Ammour, K, Bader, M, Timme, S, Kuehs, M, Csanadi, A, Kayser, G, Kohler, I, Bausch, D, Hoeppner, J, Hopt, UT, Keck, T, Stickeler, E, Passlick, B, Schilling, O, Reiss, CP, Vashist, Y, Brabletz, T, Berger, J, Lotz, J, Olesch, J, Werner, M, Wellner, UF
Format: Article
Language:English
Subjects:
Adenocarcinoma - pathology
Biomarkers, Tumor - analysis
cancer cell invasion
Epithelial-Mesenchymal Transition
human adenocarcinoma
Humans
Imaging, Three-Dimensional
Immunohistochemistry
Neoplasm Invasiveness - pathology
three-dimensional reconstruction
tumour budding
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