A Novel Gateway to InCl3 catalyzed N‐Formylation of Amines: An Access to 2‐unsubstituted, N‐unsubstituted Benzimidazoles

This article deals with a simple indium(III) chloride catalysed procedure in acetonitrile under mild condition for N‐formylation for a wide variety of amines. The reaction condition was extended to the chemoselective N‐formylation of amino groups as well. Using o‐phenylenediamines in place of mono‐a...

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Bibliographic Details
Published in:ChemistrySelect (Weinheim) 2023-07, Vol.8 (25), p.n/a
Main Authors: Sharma, Bikash, Ghosh, Anjulika, Dubey, Manoj Kumar, Bandichhor, Rakeshwar, Das, Saibal Kumar
Format: Article
Language:English
Subjects:
Amine
formic acid
formylation
indium(III) chloride
synthesis
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Summary:This article deals with a simple indium(III) chloride catalysed procedure in acetonitrile under mild condition for N‐formylation for a wide variety of amines. The reaction condition was extended to the chemoselective N‐formylation of amino groups as well. Using o‐phenylenediamines in place of mono‐amines, unsubstituted 1H‐benzimidazoles could also be accessed. This article deals with a simple indium(III) chloride catalysed procedure in acetonitrile under mild condition for N‐formylation for a wide variety of amines. The reaction condition was extended to the chemoselective N‐formylation of amino groups as well. Using o‐phenylenediamines in place of mono‐amines, unsubstituted 1H‐benzimidazoles could also be accessed.
ISSN:2365-6549
2365-6549
DOI:10.1002/slct.202300443