Melatonin alleviates inflammasome‐induced pyroptosis through inhibiting NF‐κB/GSDMD signal in mice adipose tissue

Pyroptosis is a proinflammatory form of cell death that is associated with pathogenesis of many chronic inflammatory diseases. Melatonin is substantially reported to possess anti‐inflammatory properties by inhibiting inflammasome activation. However, the effects of melatonin on inflammasome‐induced...

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Bibliographic Details
Published in:	Journal of pineal research 2017-08, Vol.63 (1), p.n/a
Main Authors:	Liu, Zhenjiang, Gan, Lu, Xu, Yatao, Luo, Dan, Ren, Qian, Wu, Song, Sun, Chao
Format:	Article
Language:	English
Subjects:	adipocyte Adipose Tissue - drug effects Adipose Tissue - metabolism Animals Apoptosis Regulatory Proteins - metabolism GSDMD inflammasome Inflammasomes - drug effects Inflammasomes - metabolism Male melatonin Melatonin - pharmacology Mice Mice, Inbred C57BL NF-kappa B - metabolism NF‐κB pyroptosis Pyroptosis - drug effects
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