Abstract 14350: Hemoptysis as a Side Effect of Cryoballoon Pulmonary Vein Isolation in Atrial Fibrillation - A Retrospective Case-control Study

• Published in: Circulation (New York, N.Y.) N.Y.), 2016-11, Vol.134 (Suppl_1 Suppl 1), p.A14350-A14350
• Main Authors: Bullert, Kevin, Gutleben, Klaus-Jürgen, Horstkotte, Dieter, Molatta, Stephan, Körber, Britta, Noelker, Georg
• Format: Article
• Language: English
• ISSN: 0009-7322; 1524-4539

IntroductionHemoptysis and pulmonary hemorrhage are rarely described as complications of cryoballoon ablation for pulmonary vein isolation (CB PVI). We aimed to evaluate a large single center cohort regarding frequency and possible risk factors for manifestation of these complications.HypothesisHemoptysis and pulmonary tissue injury are rare complications of cryoballoon pulmonary vein isolation.MethodsAmong 715 consecutive patients evaluated from a single center data base 4.3% (31 pts, 29 male, mean age 60.5 ± 11.5 years) were identified to have experienced hemoptysis following CB PVI.ResultsComparison to 31 matched controls from the same cohort revealed significantly lower ablation temperatures in the case group for the right inferior pulmonary vein (PV) (case group-56.2 ± 26.6 °C; control group49.1 ± 13.2 °C; p = 0.004) and left inferior PV(case group -56.4 ± 11.9 °C; control group 47.2 ± 7.6 °C; p = 0.001) in a univariate analysis. All other procedural parameters were found to be not significantly different between the groups. Although pre-procedural levels of hemoglobin were comparable, post-procedural hemoglobin was also lower in the case-group (case-group12.9 ± 1.6 g/dl; control-group13.7 ± 1.5 g/dl; p < 0.05). 26 pts presenting with hemoptysis underwent chest CT scan demonstrating perivenous infiltration at either the right inferior PV (n=23) or left inferior PV (n=2) or no infiltrate (n=1). No negative long-term effects were reported in follow-up scheduled at 3, 6, 12, 18 and 24 months.ConclusionsPost-procedural hemoptysis after CB PVI seems to be a relatively frequent finding associated with low freezing temperatures and pulmonary tissue infiltration predominantly located at the right inferior PV.