Abstract 15445: Excessive Daytime Sleepiness is Associated With a Higher Mortality Rate in Patients With Cardiovascular Disease

• Published in: Circulation (New York, N.Y.) N.Y.), 2018-11, Vol.138 (Suppl_1 Suppl 1), p.A15445-A15445
• Main Authors: Kim, Jeong Hwan, Dong, Tiffany, Ali, Syed, Samman Tahhan, Ayman, Hayek, Salim, Lemma, Martha, Delawalla, Shahla, Choudhary, Muaaz, Bhimani, Ravila, Alkhoder, Ayman, Bliwise, Donald, Quyyumi, Arshed
• Format: Article
• Language: English
• ISSN: 0009-7322; 1524-4539

IntroductionExcessive daytime sleepiness (EDS) has been linked to adverse cardiovascular (CV) outcomes in population-based studies but less is known about its impact in patients with coronary artery disease (CAD).HypothesisWe hypothesized that EDS, objectively assessed by Epworth Sleepiness Scale (ESS) would be associated with adverse outcomes in a dose-dependent manner in patients with CAD.MethodsESS was obtained in In 1,851 patients enrolled in the Emory Cardiovascular Biobank (mean age 65, 61% male, 26% Black), at time of procedure and followed prospectively for all-cause and CV mortality. Multivariate Cox proportional hazard models were used to examine ESS and mortality outcomes.ResultsOf the total, 45%, 34%, 15%, and 7% reported low-normal (ESS 0-5), high-normal (>5 to 10), mild-moderate (>10 to 15), and severe EDS (>15), respectively. Older age (OR=1.11 per 10 years, P=0.02), higher BMI (OR=1.16 per 5kg/m, P