Scale‐down studies for the scale‐up of a recombinant Corynebacterium glutamicum fed‐batch fermentation; loss of homogeneity leads to lower levels of cadaverine production

BACKGROUNDThe loss of efficiency and performance of bioprocesses on scale‐up is well known, but not fully understood. This work addresses this problem, by studying the effect of some fermentation gradients (pH, glucose and oxygen) that occur at the larger scale in a bench‐scale two‐compartment react...

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Bibliographic Details

Main Authors:	Williams Olughu, Alvin Nienow, Christopher Hewitt, Chris Rielly
Format:	Default Article
Published:	2019
Subjects:	Biotechnology Biochemical engineering Bioprocesses Fermentation Industrial biotechnology Process Development
Online Access:	https://hdl.handle.net/2134/10000706.v1
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