[18F]ZCDD083: A PFKFB3-Targeted PET Tracer for Atherosclerotic Plaque Imaging

: PFKFB3, a glycolysis-related enzyme upregulated in inflammatory conditions and angiogenesis, is an emerg-ing target for diagnosis and therapy of atherosclerosis. The fluorinated phenoxindazole [18F]ZCDD083 was syn-thesised, radiolabelled in 17 ±5% radiochemical yield and >99% radiochemical puri...

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Bibliographic Details

Main Authors:	Carlo De Dominicis, Paola Perrotta, Sergio Dall’Angelo, Leonie Wyffels, Steven Staelens, GRY De Meyer, Matteo Zanda
Format:	Default Article
Published:	2020
Subjects:	Organic chemistry not elsewhere classified Medicinal and Biomolecular Chemistry Pharmacology and Pharmaceutical Sciences Atherosclerosis Plaque Fluorine PET imaging glycolysis preclinical Organic Chemistry
Online Access:	https://hdl.handle.net/2134/12409187.v1
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