The discovery of novel antitrypanosomal 4-phenyl-6-(pyridin-3-yl)pyrimidines

Human African trypanosomiasis, or sleeping sickness, is a neglected tropical disease caused by Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense which seriously affects human health in Africa. Current therapies present limitations in their application, parasite resistance, or require f...

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Main Authors:	William J. Robinson, Annie E. Taylor, Solange Lauga-Cami, George Weaver, Randolph R.J. Arroo, Marcel Kaiser, Sheraz Gul, Maria Kuzikov, Bernhard Ellinger, Kuldip Singh, Tanja Schirmeister, Adolfo Botana, Chatchakorn Eurtivong, Avninder S. Bhambra
Format:	Default Article
Published:	2020
Subjects:	Organic chemistry not elsewhere classified Antitrypanosomal Sleeping sickness Human african trypanosomiasis Trypanosoma brucei rhodesiense Pyrimidines Rhodesain Docking ADME-Tox Organic Chemistry
Online Access:	https://hdl.handle.net/2134/13185032.v1
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