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Addition of pectin-alginate to a carbohydrate beverage does not maintain gastrointestinal barrier function during exercise in hot-humid conditions better than carbohydrate ingestion alone
The objective of this study was to compare the effects of consuming a 16% maltodextrin+fructose+pectin-alginate (MAL+FRU+PEC+ALG) drink against a nutrient-matched maltodextrin+fructose (MAL+FRU) drink on enterocyte damage and gastrointestinal permeability after cycling in hot and humid conditions. F...
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| Main Authors: | , , , , , , , |
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| Format: | Default Article |
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2020
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| Online Access: | https://hdl.handle.net/2134/13234892.v1 |
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| _version_ | 1822540765208772608 |
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| author | Tessa R. Flood Stefano Montanari Marley Wicks Jack Blanchard Holly Sharp Lee Taylor Matthew R. Kuennen Ben J. Lee |
| author_facet | Tessa R. Flood Stefano Montanari Marley Wicks Jack Blanchard Holly Sharp Lee Taylor Matthew R. Kuennen Ben J. Lee |
| author_sort | Tessa R. Flood (9646519) |
| collection | Figshare |
| description | The objective of this study was to compare the effects of consuming a 16% maltodextrin+fructose+pectin-alginate (MAL+FRU+PEC+ALG) drink against a nutrient-matched maltodextrin+fructose (MAL+FRU) drink on enterocyte damage and gastrointestinal permeability after cycling in hot and humid conditions. Fourteen recreational cyclists (7 men) completed 3 experimental trials in a randomized placebo-controlled design. Participants cycled for 90 min (45% maximal aerobic capacity) and completed a 15-min time-trial in hot (32 °C) humid (70% relative humidity) conditions. Every 15 min, cyclists consumed 143 mL of either (i) water; (ii) MAL+FRU+PEC+ALG (90 g·h−1 CHO/16% w/v); or (iii) a ratio-matched MAL+FRU drink (90 g·h−1 CHO/ 16% w/v). Blood was sampled before and after exercise and gastrointestinal (GI) permeability, which was determined by serum measurements of intestinal fatty acid binding protein (I-FABP) and the percent ratio of lactulose (5 g) to rhamnose (2 g) recovered in postexercise urine. Compared with water, I-FABP decreased by 349 ± 67pg·mL−1 with MAL+FRU+PEC+ALG (p = 0.007) and by 427 ± 56 pg·mL−1 with MAL+FRU (p = 0.02). GI permeability was reduced in both the MAL+FRU+PEC+ALG (by 0.019 ± 0.01, p = 0.0003) and MAL+FRU (by 0.014 ± 0.01, p = 0.002) conditions relative to water. In conclusion, both CHO beverages attenuated GI barrier damage to a similar extent relative to water. No metabolic, cardiovascular, thermoregulatory, or performance differences were observed between the CHO beverages. |
| format | Default Article |
| id | rr-article-13234892 |
| institution | Loughborough University |
| publishDate | 2020 |
| record_format | Figshare |
| spelling | rr-article-132348922020-05-04T00:00:00Z Addition of pectin-alginate to a carbohydrate beverage does not maintain gastrointestinal barrier function during exercise in hot-humid conditions better than carbohydrate ingestion alone Tessa R. Flood (9646519) Stefano Montanari (9646522) Marley Wicks (9646524) Jack Blanchard (9646525) Holly Sharp (9646528) Lee Taylor (2816005) Matthew R. Kuennen (9646531) Ben J. Lee (5544623) alginate hydrogel carbohydrate cycling heat I-FABP gastrointestinal symptoms The objective of this study was to compare the effects of consuming a 16% maltodextrin+fructose+pectin-alginate (MAL+FRU+PEC+ALG) drink against a nutrient-matched maltodextrin+fructose (MAL+FRU) drink on enterocyte damage and gastrointestinal permeability after cycling in hot and humid conditions. Fourteen recreational cyclists (7 men) completed 3 experimental trials in a randomized placebo-controlled design. Participants cycled for 90 min (45% maximal aerobic capacity) and completed a 15-min time-trial in hot (32 °C) humid (70% relative humidity) conditions. Every 15 min, cyclists consumed 143 mL of either (i) water; (ii) MAL+FRU+PEC+ALG (90 g·h<sup>−1</sup> CHO/16% w/v); or (iii) a ratio-matched MAL+FRU drink (90 g·h<sup>−1</sup> CHO/ 16% w/v). Blood was sampled before and after exercise and gastrointestinal (GI) permeability, which was determined by serum measurements of intestinal fatty acid binding protein (I-FABP) and the percent ratio of lactulose (5 g) to rhamnose (2 g) recovered in postexercise urine. Compared with water, I-FABP decreased by 349 ± 67pg·mL<sup>−1</sup> with MAL+FRU+PEC+ALG (p = 0.007) and by 427 ± 56 pg·mL<sup>−1</sup> with MAL+FRU (p = 0.02). GI permeability was reduced in both the MAL+FRU+PEC+ALG (by 0.019 ± 0.01, p = 0.0003) and MAL+FRU (by 0.014 ± 0.01, p = 0.002) conditions relative to water. In conclusion, both CHO beverages attenuated GI barrier damage to a similar extent relative to water. No metabolic, cardiovascular, thermoregulatory, or performance differences were observed between the CHO beverages. 2020-05-04T00:00:00Z Text Journal contribution 2134/13234892.v1 https://figshare.com/articles/journal_contribution/Addition_of_pectin-alginate_to_a_carbohydrate_beverage_does_not_maintain_gastrointestinal_barrier_function_during_exercise_in_hot-humid_conditions_better_than_carbohydrate_ingestion_alone/13234892 CC BY-NC-ND 4.0 |
| spellingShingle | alginate hydrogel carbohydrate cycling heat I-FABP gastrointestinal symptoms Tessa R. Flood Stefano Montanari Marley Wicks Jack Blanchard Holly Sharp Lee Taylor Matthew R. Kuennen Ben J. Lee Addition of pectin-alginate to a carbohydrate beverage does not maintain gastrointestinal barrier function during exercise in hot-humid conditions better than carbohydrate ingestion alone |
| title | Addition of pectin-alginate to a carbohydrate beverage does not maintain gastrointestinal barrier function during exercise in hot-humid conditions better than carbohydrate ingestion alone |
| title_full | Addition of pectin-alginate to a carbohydrate beverage does not maintain gastrointestinal barrier function during exercise in hot-humid conditions better than carbohydrate ingestion alone |
| title_fullStr | Addition of pectin-alginate to a carbohydrate beverage does not maintain gastrointestinal barrier function during exercise in hot-humid conditions better than carbohydrate ingestion alone |
| title_full_unstemmed | Addition of pectin-alginate to a carbohydrate beverage does not maintain gastrointestinal barrier function during exercise in hot-humid conditions better than carbohydrate ingestion alone |
| title_short | Addition of pectin-alginate to a carbohydrate beverage does not maintain gastrointestinal barrier function during exercise in hot-humid conditions better than carbohydrate ingestion alone |
| title_sort | addition of pectin-alginate to a carbohydrate beverage does not maintain gastrointestinal barrier function during exercise in hot-humid conditions better than carbohydrate ingestion alone |
| topic | alginate hydrogel carbohydrate cycling heat I-FABP gastrointestinal symptoms |
| url | https://hdl.handle.net/2134/13234892.v1 |