Development of a bone-mimetic 3D printed Ti6Al4V scaffold to enhance osteoblast-derived extracellular vesicles’ therapeutic efficacy for bone regeneration

Extracellular Vesicles (EVs) are considered promising nanoscale therapeutics for bone regeneration. To date, EVs are typically procured from cells on 2D tissue culture plastic, an artificial environment that limits cell growth and does not replicate in situ biochemical or biophysical conditions. Thi...

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Bibliographic Details
Main Authors: Kenny Man, Mathieu Y Brunet, Sophie Louth, Thomas E Robinson, Maria Fernandez-Rhodes, Soraya Williams, Angelica S Federici, Owen Davies, David A Hoey, Sophie C Cox
Format: Default Article
Published: 2021
Subjects:
3D printing
titanium
extracellular vesicles
osteogenesis
tissue engineering
Online Access:https://hdl.handle.net/2134/16870697.v1
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