Use of wet milling combined with temperature cycling to minimize crystal agglomeration in a sequential antisolvent-cooling crystallization

The objective of the research was to improve the process design of a combined anti-solvent/cooling crystallization to reduce the degree of agglomeration of a real active pharmaceutical ingredient product, manufactured using a crystallization stage employing a methanol/water solvent system. Knowledge...

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Bibliographic Details

Main Authors:	Zhuang Sun, Justin Quon, Charles Papageorgiou, Brahim Benyahia, Chris Rielly
Format:	Default Article
Published:	2022
Subjects:	Inorganic chemistry not elsewhere classified Inorganic & Nuclear Chemistry Physical Chemistry (incl. Structural) Materials Engineering Inorganic Chemistry
Online Access:	https://hdl.handle.net/2134/20272002.v1
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