A combined D-optimal and estimability model-based design of experiments of a batch cooling crystallization process

In this work, a systematic methodology is proposed to help develop model-based design of experiments to build robust and reliable mathematical model of a batch crystallization process. The cooling crystallization of paracetamol in water and propanol is used as the case study. The mathematical model...

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Bibliographic Details
Main Authors: Xuming Yuan, Brahim Benyahia
Format: Default Book chapter
Published: 2023
Subjects:
Chemical engineering
Environmental engineering
Resources engineering and extractive metallurgy
Structural Identifiability
Estimability
Sensitivity Analysis
Model-Based Design of Experiment (MBDoE)
Temperature Cycling
Batch Crystallization
Online Access:https://hdl.handle.net/2134/24378325.v1
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