Novel 4-[4-(4-methylpiperazin-1-yl)phenyl]-6-arylpyrimidine derivatives and their antitrypanosomal activities against T.brucei

Human African trypanosomiasis, or sleeping sickness, is a neglected tropical disease caused by Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense and is invariably fatal unless treated. Current therapies present limitations in their application, parasite resistance, or require further c...

Full description

Bibliographic Details

Main Authors:	Annie E Taylor, Moritz Hering, Mark Elsegood, Simon J Teat, George Weaver, Randolph RJ Arroo, Marcel Kaiser, Pascal Maeser, Avninder S Bhambra
Format:	Default Article
Published:	2024
Subjects:	Pharmacology and pharmaceutical sciences Medicinal and biomolecular chemistry Organic chemistry Medicinal & Biomolecular Chemistry Antitrypanosomal Pyrimidines Antiparasitic Kinetoplastid Neglected tropical diseases T.brucei
Online Access:	https://hdl.handle.net/2134/25974946.v1
Tags:	Add Tag No Tags, Be the first to tag this record!