Insight into the large-scale upstream fermentation environment using scaled-down models

Scaled‐down models are small‐scale bioreactors, used to mimic the chemical (pH, nutrient and dissolved oxygen) and physical (pressure, viscosity and temperature) gradients known to occur in the large‐scale fermenter. Conventionally, before scaling up any bioprocess, small‐scale bioreactors are used...

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Bibliographic Details
Main Authors: Williams Olughu, Gurjot Deepika, Christopher J. Hewitt, Chris Rielly
Format: Default Article
Published: 2018
Subjects:
Chemical engineering not elsewhere classified
Scale‐up
Scale‐down model
Heterogenous cell population
Large‐scale inhomogeneity
High throughput fermentation
Bioprocess
Chemical Engineering not elsewhere classified
Online Access:https://hdl.handle.net/2134/35107
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https://hdl.handle.net/2134/35107

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