Transferrin-modified doxorubicin-loaded biodegradable nanoparticles exhibit enhanced efficacy in treating brain glioma-bearing rats

Doxorubicin (Dox) is widely used for the treatment of solid tumors but its clinical utility on glioma is limited. In this study, we developed a novel nano-scale drug delivery system employing biodegradable nanoparticle (NP) as carriers to load Dox. Transferrin (Tf) was conjugated to the surface of N...

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Bibliographic Details

Main Authors:	Guodong Liu, Jinning Mao, Zirong Jiang, Tao Sun, Yunfeng Hu, Zhen Jiang, Caiyuan Zhang, Jun Dong, Qiang Huang, Qing Lan
Format:	Default Article
Published:	2013
Subjects:	Chemical engineering not elsewhere classified untagged Chemical Engineering not elsewhere classified
Online Access:	https://hdl.handle.net/2134/24938
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