A new paradigm for numerical simulation of microneedle based drug delivery aided by histology of microneedle pierced skin

Microneedle (MN) is a relatively recent invention and an efficient technology for transdermal drug delivery (TDD). Conventionally, mathematical models of MNs drug delivery define the shape of the holes created by the MNs in the skin as the same as their actual geometry. Furthermore, the size of the...

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Bibliographic Details
Main Authors: Tao Han, Diganta Das
Format: Default Article
Published: 2015
Subjects:
Chemical engineering not elsewhere classified
Transdermal drug delivery
Microneedles
Numerical modeling and simulation
Histological image
Diffusion
Canny edge detection
Skin
Permeability
Absorption
Chemical Engineering not elsewhere classified
Online Access:https://hdl.handle.net/2134/17271
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