Systematic microcarrier screening and agitated culture conditions improves human mesenchymal stem cell yield in bioreactors

Production of human mesenchymal stem cells for allogeneic cell therapies requires scalable, cost-effective manufacturing processes. Microcarriers enable the culture of anchorage-dependent cells in stirred-tank bioreactors. However, no robust, transferable methodology for microcarrier selection exist...

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Bibliographic Details

Main Authors:	Qasim A. Rafiq, Karen Coopman, Alvin W. Nienow, Christopher J. Hewitt
Format:	Default Article
Published:	2016
Subjects:	Chemical engineering not elsewhere classified Human mesenchymal stem cell Cell therapy bioprocessing Microcarrier Bioreactor Regenerative medicine Chemical Engineering not elsewhere classified
Online Access:	https://hdl.handle.net/2134/19978
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