Development of a multi-step synthesis and workup sequence for an integrated, continuous manufacturing process of a pharmaceutical

The development and operation of the synthesis and workup steps of a fully integrated, continuous manufacturing plant for synthesizing aliskiren, a small molecule pharmaceutical, are presented. The plant started with advanced intermediates, two synthetic steps away from the final active pharmaceutic...

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Main Authors:	Patrick L. Heider, S.C. Born, S. Basak, Brahim Benyahia, Richard Lakerveld, Haitao Zhang, R. Hogan, L. Buchbinder, Aaron Wolfe, Salvatore Mascia, James M.B. Evans, Timothy F. Jamison, Klavs F. Jensen
Format:	Default Article
Published:	2014
Subjects:	Chemical engineering not elsewhere classified untagged Chemical Engineering not elsewhere classified
Online Access:	https://hdl.handle.net/2134/17593
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