Microencapsulation of salmonella-specific bacteriophage Felix O1 using spray-drying in a pH-responsive formulation and direct compression tableting of powders into a solid oral dosage form

The treatment of enteric bacterial infections using oral bacteriophage therapy can be challenging since the harsh acidic stomach environment renders phages inactive during transit through the gastrointestinal tract. Solid oral dosage forms allowing site-specific gastrointestinal delivery of high dos...

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Bibliographic Details

Main Authors:	Gurinder K. Vinner, Zahra Rezaie-Yazdi, Miika Leppanen, Andy Stapley, Mark Leaper, Danish Malik
Format:	Default Article
Published:	2019
Subjects:	Chemical engineering not elsewhere classified Antibiotic resistance Bacteriophages Direct compression Microparticles pH-responsive Salmonella Spray drying Tablets Chemical Engineering not elsewhere classified
Online Access:	https://hdl.handle.net/2134/37530
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