Culture of human mesenchymal stem cells on microcarriers in a 5 l stirred-tank bioreactor

For the first time, fully functional human mesenchymal stem cells (hMSCs) have been cultured at the litre-scale on microcarriers in a stirred-tank 5 l bioreactor, (2.5 l working volume) and were harvested via a potentially scalable detachment protocol that allowed for the successful detachment of hM...

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Bibliographic Details

Main Authors:	Qasim Rafiq, Kathryn Brosnan, Karen Coopman, Alvin W. Nienow, Christopher Hewitt
Format:	Default Article
Published:	2013
Subjects:	Chemical engineering not elsewhere classified Bioreactor Human mesenchymal stem cells Metabolite profiles microcarriers Proliferation Regenerative medicine bioprocessing Spinner-flask Chemical Engineering not elsewhere classified
Online Access:	https://hdl.handle.net/2134/14778
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