Microneedle assisted micro-particle delivery from gene guns: experiments using skin-mimicking agarose gel

A set of laboratory experiments has been carried out to determine if micro-needles (MNs) can enhance penetration depths of high-speed micro-particles delivered by a type of gene gun. The micro-particles were fired into a model target material, agarose gel, which was prepared to mimic the viscoelasti...

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Bibliographic Details
Main Authors: Dongwei Zhang, Diganta Das, Chris Rielly
Format: Default Article
Published: 2014
Subjects:
Chemical engineering not elsewhere classified
Gene gun
Stainless steel micro-particles
Micro-needle
Penetration depth
Agarose gel
Particle size
Biocompatability
Biomaterials
Transdermal drug delivery
Skin
Chemical Engineering not elsewhere classified
Online Access:https://hdl.handle.net/2134/14356
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