Use of orbital shaken disposable bioreactors for mammalian cell cultures from the milliliter-scale to the 1,000-liter scale

Driven by the commercial success of recombinant biopharmaceuticals, there is an increasing demand for novel mammalian cell culture bioreactor systems for the rapid production of biologicals that require mammalian protein processing. Recently, orbitally shaken bioreactors at scales from 50 mL to 1,00...

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Bibliographic Details

Main Authors:	Xiaowei Zhang, Matthieu Stettler, Dario De Sanctis, Marco Perrone, Nicola Parolini, Marco Discacciati, Maria De Jesus, David Hacker, Alfio Quarteroni, Florian M. Wurm
Format:	Default Book chapter
Published:	2009
Subjects:	Other mathematical sciences not elsewhere classified Disposable bioreactor Mammalian cell culture Orbital shaking Oxygen transfer rate Scale-up Shaken bioreactor Mathematical Sciences not elsewhere classified
Online Access:	https://hdl.handle.net/2134/18752
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